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Adiposity Linked to Aggressive Prostate Cancer and Death

Adiposity Linked to Aggressive Prostate Cancer and Death GOTHENBURG, Sweden — Obese men, ie those with a high body mass index (BMI) and large waist circumference, have a greater risk of both high-grade, aggressive prostate cancer and prostate-cancer death than men with normal BMI and waist circumference, new data from a large European study reveals. The study of over 140,000 men from eight countries showed that there was a linear association between BMI and waist circumference and high-grade prostate cancer and prostate-cancer death, with the risks increasing by more than 10% with each stepwise increase in adiposity. Another notable finding from the investigation, which was presented at the European Obesity Summit 2016, was that, paradoxically, the overall risk of prostate cancer was lower for men with a higher BMI and those with a larger waist circumference.